Pictures
MD Droplet
All-atom MD simulation of complex coacervates formed by ProTa and H1
Droplet-based microfluidic mixer
H1 on the Nucleosome
ProTa Extracts H1 from the Nucleosome
Competitive Substitution on the Nucleosome
Enhancing nsFCS with Nanophotonics
All-atom MD of disordered peptide
Competitive substitution of H1 and ProTa (Sottini et al. 2020)
Competitive Substitution via ternary complex formation of H1 and ProTa (Sottini et al. 2020)
Competitive substitution via ternary complex formation of H1 and ProTa without exchange (Sottini et al. 2020)Competitive substitution via ternary complex formation of H1 and ProTa without exchange (Sottini et al. 2020)
The spectrum of disorder in protein complexes (Schuler et al. 2020)
Simulation of the highly disordered H1-ProTa complex (Borgia et al. 2018)
Principal component analysis of the highly disordered H1-ProTa complex (Borgia et al. 2018)
Single-molecule FRET of coupled folding and binding (Zosel et al. 2018)
Proline cis/trans isomerization modulates coupled folding and binding (Zosel et al. 2018)
Transition path time measurements reveal an encounter complex in coupled forlding and binding (Sturzenegger et al., 2018)
Simulation of Nucleic Acid Chaperoning by a Disordered Protein (Holmstrom et al. 2019)
Simulation of Nucleic Acid Chaperoning by a Disordered Protein (Holmstrom et al. 2019)
Rapid microfluidic dilution device (Zijlstra et al. 2017)
Double-jump microfluidic mixing device (Dingfelder et al. 2017)
Microfluidic mixing device, inlet filter (electron micrograph, Wunderlich et al. 2013)
Fluorescence lifetime imaging of microinjected adherent cells (Koenig et al. 2015)
Single-molecule spectroscopy in live eukaryotic cells (Koenig et al. 2015)
Folding and misfolding in tandem repeat domains (Borgia et al. 2015)
Integrative investigation of denaturant-induced unfolded-state expansion (Borgia et al. 2016)
Polymer effects in macromolecular crowding (Soranno et al. 2014)
Time-resolved transfer efficiency histograms of ClyA protomer formation (Benke et al. 2015)
ClyA cytolytic pore assembly mechanism (Benke et al. 2015)
Mixing region of a microfluidic mixing device (electron micrograph, Wunderlich et al. 2013)
Finite-element calculations of microfluidic mixing by hydrodynamic focusing (Wunderlich et al. 2013)
Microfluidic mixing device (electron micrograph, Wunderlich 2013)
Polymer scaling laws of unfolded and intrinsically disordered proteins (Hofmann et al. 2012)
Chaperone-mediated protein expansion (Kellner et al., 2014)
Mapping denaturant-induced unfolded state expansion (Aznauryan et al. 2016)
Singlet-singlet annihilation detected by correlation spectroscopy (Nettels et al. 2015)
Taylor dispersion in rapid microfluidic mixing (Finite-element calculations, Wunderlich et al. 2012)
Microfluidic deflection device (Finite-element calculation, Wunderlich, unpublished)
Design cycle for microfluidics (Wunderlich, unpublished)
Four-channel confocal single-molecule instrument (Plitzko et al. 2017)
Laser spectroscopy of single molecules
Förster resonance energy transfer (Schuler 2013)
FRET on the cold shock protein
Timescales accessible with single-molecule spectroscopy (adapted from Hofmann & Schuler 2013)
Free-energy landscape